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- Tasks: Join a team developing innovative proteins for carbon upcycling and sustainability.
- Company: Be part of the Open Bioeconomy Lab at the University of Cambridge, leading in bioengineering research.
- Benefits: Enjoy a collaborative environment with opportunities for professional growth and impactful work.
- Why this job: Contribute to cutting-edge research that tackles climate change and promotes sustainability.
- Qualifications: PhD or pursuing one in synthetic biology; experience in protein engineering and lab automation required.
- Other info: Fixed-term position until March 2028; applications close on 15th June 2025.
The predicted salary is between 28800 - 48000 £ per year.
Overview
Short Term Position (3 months Full time/part time) in Protein Engineering. Applications are invited for a Research Assistant/Research Associate to work with Professor Lisa Hall on a project entitled HANDI-NAT: Nucleic acid amplification of microbial load in drinking water supply— a project funded by the Leverhulme Trust, designing a self-reporting Bst polymerase for use in Loop Mediated Nucleic Acid Amplification (LAMP). The project will be undertaken together with Professor Alex Routh’s group in the Department of Chemical Engineering and Biotechnology. The project seeks to design a field-useable low-cost nucleic acid test for microbial load in community drinking water supplies in low and middle income countries (LMICs). It addresses the UN 2030 Sustainable Development Goal identifying water inequality as a priority to “ensure availability and sustainable management of water and sanitation for all”.
The post holder will bring together the final components of an engineered Bst polymerase to test its performance in LAMP reactions and its capacity to give a direct colorimetric signal linked with microbial contamination. Candidates should be expert in engineering of proteins and proficient in nucleic acid testing and molecular biology. They should have a PhD or at least 3 years experience in a relevant area, with a strong underpinning understanding and laboratory expertise in the enabling techniques.
Responsibilities
- To optimise and adjust (as required) the designed Bst polymerase fusion protein.
- Build the fusion constructs.
- Develop the testing protocol to establish detection limits for some model microbial contaminants.
- If time allows: Undertake some field trials at UK based sites of environmental interest, prior to delivering the system to collaborators in LMICs.
Fixed-term
The funds for this post are available for 3 months in the first instance.
Application process
Apply online via the recruitment system. Please quote reference NQ48650 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Further information
Further particulars for more information please see the Further Particulars.
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Research Assistant/Research Associate (Fixed Term) employer: Cambridge University Department of Chemical Engineering and Biotechnology
Contact Detail:
Cambridge University Department of Chemical Engineering and Biotechnology Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Research Assistant/Research Associate (Fixed Term)
✨Tip Number 1
Familiarise yourself with the latest research in synthetic biology and protein engineering. This will not only help you understand the role better but also allow you to engage in meaningful conversations during interviews, showcasing your passion and knowledge.
✨Tip Number 2
Network with professionals in the field, especially those connected to the Open Bioeconomy Lab or similar projects. Attend relevant conferences or webinars to meet potential colleagues and learn more about ongoing research, which can give you an edge in your application.
✨Tip Number 3
Prepare to discuss your hands-on experience with cell-free protein expression systems and lab automation. Be ready to provide specific examples of your work and how it relates to the goals of the EngZyme project, as this will demonstrate your practical skills and relevance to the role.
✨Tip Number 4
Reach out to Dr Jenny Molloy for an informal chat about the position. This shows initiative and genuine interest in the role, plus it gives you a chance to ask questions that could help you tailor your approach when applying.
We think you need these skills to ace Research Assistant/Research Associate (Fixed Term)
Some tips for your application 🫡
Understand the Role: Read the job description thoroughly to grasp the specific requirements and responsibilities of the Research Assistant/Research Associate position. Pay attention to the qualifications needed, such as a PhD or progress towards one, and the skills in synthetic biology and protein engineering.
Tailor Your CV: Customise your CV to highlight relevant experience in cell-free protein expression systems, protein engineering, and lab automation. Make sure to include any hands-on experience with computational protein design and engineering, as these are key aspects of the role.
Craft a Strong Cover Letter: Write a compelling cover letter that connects your background and skills to the specific project, 'EngZyme'. Emphasise your teamwork abilities, communication skills, and problem-solving capabilities, as these are essential for the role.
Follow Application Instructions: Ensure you follow all application instructions carefully. Register an account on the recruitment system, quote the reference NQ46023 in your application, and submit all required documents before the closing date of 15th June 2025.
How to prepare for a job interview at Cambridge University Department of Chemical Engineering and Biotechnology
✨Know Your Research
Familiarise yourself with the specifics of the EngZyme project and the Open Bioeconomy Lab. Understanding the goals and methodologies of the research will allow you to engage in meaningful discussions during the interview.
✨Highlight Relevant Experience
Be prepared to discuss your experience with cell-free protein expression systems, protein engineering, and lab automation. Use specific examples from your past work to demonstrate your skills and how they relate to the role.
✨Showcase Teamwork and Independence
The role requires both collaborative and independent work. Prepare examples that illustrate your ability to work effectively in a team as well as your capability to take initiative and solve problems on your own.
✨Prepare Questions
Have thoughtful questions ready for your interviewers about the project, team dynamics, and future directions of the research. This shows your genuine interest in the position and helps you assess if it's the right fit for you.
