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- Tasks: Lead antibody characterization workflows and collaborate on innovative ADC formats.
- Company: Join a cutting-edge biotech company revolutionizing cancer care with proprietary Antibody-Drug Conjugates.
- Benefits: Enjoy competitive pay, 30 days holiday, private health insurance, and performance bonuses.
- Why this job: Make a real impact in oncology while working in a dynamic, collaborative environment.
- Qualifications: BSc/MSc in Life Sciences or Chemistry; expertise in mass spectrometry and analytical techniques required.
- Other info: Hybrid work model available; be part of groundbreaking R&D in state-of-the-art labs.
The predicted salary is between 48000 - 72000 £ per year.
Senior Analytical Scientist – Mass Spectrometry – Antibody Drug Conjugates
Location: London, UK (Hybrid)
Are you ready to revolutionize oncology treatments? Join an innovative biotech company at the forefront of developing proprietary Antibody-Drug Conjugates (ADCs) that are redefining cancer care. With a strong pipeline of clinical and preclinical programs, this company is blending expertise in antibody engineering, bioconjugation, and analytical sciences to deliver life-changing therapies.
Their state-of-the-art labs are the epicenter of groundbreaking R&D, and they’re seeking a talented Senior Analytical Scientist to drive the development of next-generation ADCs, using cutting-edge analytical techniques and mass spectrometry.
Your Role:
- Lead the development of robust antibody characterization workflows, including stress testing, sequence liability analysis, and PTM/glycan profiling.
- Collaborate with Bioconjugation and Downstream Manufacturing teams to optimize analytical protocols, including drug-to-antibody ratio (DAR) determinations.
- Partner with Antibody Engineering to innovate and characterize novel antibody and ADC formats.
- Keep meticulous records of experiments and foster seamless communication across interdisciplinary teams.
- Play a pivotal role in a cross-functional project team, advancing preclinical ADC assets through the early stages of drug discovery.
Your Expertise:
- Qualifications: BSc/MSc in Life Sciences or Chemistry with a strong foundation in Biochemistry.
- Analytical Skills: Mastery of mass spectrometry techniques (e.g., peptide mapping, DAR determination), proficiency with tools like MassHunter and Agilent systems.
- Technical Proficiency: Expertise in LC-MS, HIC-HPLC, SEC, IEX, and RP-HPLC; experience with Chromeleon and Vanquish UHPLC systems is a bonus.
- Track Record: Demonstrated ability to develop and troubleshoot analytical methods for protein and conjugate characterization.
- Collaboration: Excellent interpersonal and communication skills, thriving in multidisciplinary environments.
- Industry Savvy: Experience in biotech or industry settings.
Bonus Points For:
- HPLC expertise in protein quantitation, charge variant analysis, and glycan profiling.
- Small molecule mass spectrometry, including payload cleavage studies.
- Hands-on experience with AKTA purification systems and Unicorn software.
- Familiarity with biomolecule tracking software like Genedata Biologics.
What’s In It for You?
This role comes with a competitive benefits package, including:
- Annual travel allowance and performance-based bonus.
- 30 days of holiday plus bank holidays, with an additional Christmas shutdown.
- Matched pension contributions, private health insurance, share options, and social incentives.
Why Join?
Be part of a dynamic, forward-thinking team that values scientific innovation and collaboration. This is your chance to work on transformative oncology therapies, expand your expertise, and contribute to a mission that truly makes a difference.
Take the next step in your career—apply now and help shape the future of cancer treatment!
Senior Analytical Scientist employer: BioTalent
Contact Detail:
BioTalent Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Analytical Scientist
✨Tip Number 1
Familiarize yourself with the latest advancements in mass spectrometry techniques, especially those relevant to antibody-drug conjugates. This knowledge will not only enhance your understanding but also demonstrate your commitment to staying at the forefront of analytical science.
✨Tip Number 2
Network with professionals in the biotech industry, particularly those working with ADCs. Attend relevant conferences or webinars to connect with potential colleagues and learn about the latest trends and challenges in the field.
✨Tip Number 3
Showcase your collaborative skills by discussing past experiences where you successfully worked in cross-functional teams. Highlight how you contributed to projects that required input from various disciplines, as this is crucial for the role.
✨Tip Number 4
Prepare to discuss specific analytical methods you've developed or troubleshot in previous roles. Being able to articulate your hands-on experience with techniques like LC-MS and HPLC will set you apart from other candidates.
We think you need these skills to ace Senior Analytical Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in mass spectrometry and analytical techniques. Emphasize your expertise in antibody characterization workflows and any specific projects that align with the job description.
Craft a Compelling Cover Letter: Write a cover letter that showcases your passion for oncology treatments and your understanding of Antibody-Drug Conjugates. Mention how your skills and experiences make you a perfect fit for the role and the company's mission.
Highlight Collaborative Experience: Since the role involves working with cross-functional teams, be sure to include examples of your collaborative work in previous positions. Describe how you effectively communicated and contributed to team goals.
Showcase Technical Proficiency: Detail your technical skills related to mass spectrometry and other analytical techniques mentioned in the job description. Include specific tools and systems you have experience with, such as MassHunter, LC-MS, and HPLC.
How to prepare for a job interview at BioTalent
✨Showcase Your Analytical Skills
Be prepared to discuss your mastery of mass spectrometry techniques and how you've applied them in previous roles. Highlight specific examples of peptide mapping or DAR determination that demonstrate your expertise.
✨Emphasize Collaboration Experience
Since this role involves working with various teams, share experiences where you successfully collaborated with bioconjugation or downstream manufacturing teams. Discuss how you optimized analytical protocols together.
✨Demonstrate Technical Proficiency
Familiarize yourself with the tools mentioned in the job description, such as MassHunter and Agilent systems. Be ready to explain how you've used LC-MS, HIC-HPLC, and other techniques in your past work.
✨Prepare for Problem-Solving Questions
Expect questions about troubleshooting analytical methods. Prepare to discuss challenges you've faced in protein and conjugate characterization and how you overcame them, showcasing your problem-solving skills.
