Platform Engineer - HPC / High Performance Computing (we have office locations in Cambridge, Leeds &

Genomics England partners with the NHS to provide whole genome sequencing diagnostics. We also equip researchers to find the causes of disease and develop new treatments — with patients and participants at the heart of it all. Our mission is to continue refining, scaling, and evolving our ability to enable others to deliver genomic healthcare and conduct genomic research. We are accelerating our impact and working with patients, doctors, scientists, government, and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

We are seeking an experienced AWS HPC Platform Engineer with a proven track record. You will lead the implementation of AWS best practices across a team of engineers developing their expertise in AWS platform engineering. Your responsibilities include supporting the live HPC cluster in AWS, ensuring its stability and performance, and collaborating closely with our infrastructure architect while focusing on core cloud-related operational activities.

• Leadership & Mentorship: Guide and mentor engineers to enhance their AWS platform engineering skills. Promote AWS best practices and drive automation standards within the team.
• HPC Cluster Support: Maintain and optimise the live HPC cluster in AWS. Collaborate with the Infrastructure Architect to ensure architectural alignment and effective implementation.
• Data Platform & Tools Support: Manage and support data ingestion tools including LSF RTM, Athena databases, and workflows. Ensure seamless integration and performance of these tools within AWS.
• Infrastructure as Code (IaC) Alignment: Work with the Infrastructure Architect to align on IaC strategies, utilising Ansible Tower and GitLab Pipelines for AWS and on-prem environments.
• Benchmarking & Healthchecks: Develop and integrate standardised benchmarking and healthchecks for the HPC, leveraging AWS capabilities.
• IOPS Monitoring Tool Integration: Support the rollout and integration of IOPS monitoring tools (Mistrel/Breeze) in AWS. Ensure these tools are effectively connected to both on-prem and AWS HPC environments.
• Cost Optimisation: Implement strategies for cost optimisation of the AWS stack in HPC.
• Vulnerability Patching: Develop creative solutions for vulnerability patching of the AWS stack in HPC, especially for large EC2 instances.
• S3 Integration: Support the integration of S3 into Double Helix to enhance cloud storage options.
• DRAGEN F2 Integration: Design and support the use of DRAGEN F2 within GEL, including creating necessary AMIs.

• Deep, hands-on experience with building compute families (GPUs, CPUs) using cloud services.
• Fluency in data storage services (S3, mount-point, data lakes, Lustre).
• Expertise in Infrastructure as Code (IaC) using Terraform and CI/CD pipelines with GitLab.
• Strong problem-solving skills and ability to see the bigger picture.
• Excellent teamwork and communication skills.

Salary from: £71,500. Being part of such a meaningful mission is rewarding, and we support our people with a comprehensive benefits package, including:

• Generous Leave: 30 days' holiday plus bank holidays, additional leave for long service, and up to 30 days of remote working abroad annually (approval required).
• Family-Friendly: Flexible working arrangements, enhanced maternity, paternity, and shared parental leave benefits.
• Pension & Financial: Defined contribution pension (Genomics England matches up to 10%), Life Assurance (3x salary), and Give As You Earn scheme.
• Learning & Development: Individual learning budgets, support for training and certifications, and reimbursement for one professional subscription annually (approval required).
• Recognition & Rewards: Employee recognition programme and referral scheme.
• Health & Wellbeing: Subsidised gym membership, Headspace access, Employee Assistance Programme, eye tests, flu jabs.

Commitment to Diversity and Inclusion: We are dedicated to creating an inclusive environment that promotes equity, diversity, and inclusion. We welcome applicants regardless of disability, ethnicity, gender, gender identity, religion, sexual orientation, or social background. Our policies prohibit discrimination, harassment, victimisation, or bullying, and we encourage applicants to request any necessary adjustments during the recruitment process.

Blended Working Model: Our hybrid working model offers flexibility, with most employees expected to work from the office at least twice a month. Locations include Canary Wharf, Cambridge, and Leeds. Specific roles may require full-time on-site presence. Teams are encouraged to tailor their working patterns to what works best for them.

Onboarding Background Checks: All successful candidates will undergo a DBS check. Applicants must disclose any previous offences, as unspent convictions may affect their application due to the nature of our healthcare work.