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- Tasks: Lead the development of innovative oncology therapeutics and influence early drug development strategies.
- Company: Join a cutting-edge start-up focused on improving cancer treatment through advanced drug discovery.
- Benefits: Be part of a dynamic team with opportunities for growth and collaboration in a start-up environment.
- Why this job: Make a meaningful impact in oncology while working with novel technologies and a passionate team.
- Qualifications: PhD in a relevant field with experience in oncology biologics, especially ADCs or Bispecific Antibodies.
- Other info: Ideal for those who thrive in fast-paced, innovative settings and enjoy building external partnerships.
The predicted salary is between 60000 - 84000 £ per year.
A fantastic opportunity has arisen for a Principal Scientist – Discovery & Translational Biology to join a high-potential drug-development start-up, who are focused on developing new oncology therapeutics that significantly improve overall survival for patients with a high unmet need. Our client is at the cutting edge of oncology therapeutics, triggering a new wave in target discovery by using proprietary algorithms to identify novel protein fingerprints from a comprehensive membrane protein database. They are in the process of establishing their own laboratory to execute their ambitious growth plans and seeking a highly motivated Principal Scientist to join their Research Group. This is an exciting opportunity for the right candidate to make a meaningful contribution across discovery and translational sciences.
KEY DUTIES AND RESPONSIBILITIES:
- Your duties as the Principal Scientist will be varied; however, the key duties and responsibilities are as follows:
- The ideal candidate will have hands-on experience in developing novel oncology therapeutics, ideally Antibody Drug Conjugates (ADCs) or Bispecific Antibodies.
- You will be adept at balancing delivery at the bench with project leadership and have a proven track record of building successful relationships with external partners.
- Joining a small team during a period of growth, this is a dynamic role that will allow the successful candidate to influence strategy on all aspects of early drug development.
- You will support the portfolio expansion through target validation and co-expression studies, develop workflows for hit selection and lead triage, and deliver pivotal in vivo proof of concept data via external partners.
ROLE REQUIREMENTS:
- To be successful in your application to this exciting role as the Principal Scientist we are looking to identify the following on your profile and past history:
- Applicants will have a PhD in a relevant field, with significant experience in the development of novel oncology biologics, ideally Antibody Drug Conjugates (ADCs) or Bispecific Antibodies, gained predominantly within a commercial biotech or biopharma environment.
- Strong technical expertise in primary cell tissue culture, flow cytometry and IHC assay development and execution. Experience working with spheroids is desirable.
- You must be comfortable working independently and pro-actively in a start-up environment.
Principal Scientist employer: Hyper Recruitment Solutions
Contact Detail:
Hyper Recruitment Solutions Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Principal Scientist
✨Tip Number 1
Network with professionals in the oncology and biopharma sectors. Attend industry conferences, webinars, or local meetups to connect with potential colleagues and learn about the latest trends in drug development.
✨Tip Number 2
Showcase your hands-on experience with Antibody Drug Conjugates (ADCs) or Bispecific Antibodies during informal discussions or networking events. This will help you stand out as a candidate who understands the specific challenges and innovations in this area.
✨Tip Number 3
Familiarise yourself with the proprietary algorithms and technologies used in target discovery. Being knowledgeable about their methods can give you an edge in conversations with the hiring team and demonstrate your genuine interest in their work.
✨Tip Number 4
Prepare to discuss your project leadership experiences and how you've successfully built relationships with external partners. Highlighting these skills will show that you're not just technically proficient but also capable of driving projects forward in a collaborative environment.
We think you need these skills to ace Principal Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your PhD and relevant experience in developing oncology biologics, particularly Antibody Drug Conjugates or Bispecific Antibodies. Use specific examples to demonstrate your technical expertise in primary cell tissue culture, flow cytometry, and IHC assay development.
Craft a Compelling Cover Letter: In your cover letter, express your enthusiasm for the role and the company’s mission. Discuss how your background aligns with their focus on oncology therapeutics and your ability to work independently in a start-up environment.
Highlight Relevant Skills: Clearly outline your hands-on experience and any successful projects you've led that relate to drug development. Mention your ability to build relationships with external partners, as this is crucial for the role.
Proofread Your Application: Before submitting, carefully proofread your application materials for any errors or inconsistencies. A polished application reflects your attention to detail and professionalism, which are essential in a scientific role.
How to prepare for a job interview at Hyper Recruitment Solutions
✨Showcase Your Technical Expertise
Be prepared to discuss your hands-on experience with oncology therapeutics, particularly Antibody Drug Conjugates and Bispecific Antibodies. Highlight specific projects where you successfully applied techniques like primary cell tissue culture, flow cytometry, and IHC assay development.
✨Demonstrate Leadership Skills
Since the role involves project leadership, share examples of how you've led teams or projects in the past. Discuss how you balanced bench work with strategic decision-making and how you built relationships with external partners.
✨Emphasise Adaptability in a Start-Up Environment
Talk about your ability to thrive in dynamic settings. Provide examples of how you've adapted to changing priorities or challenges in previous roles, showcasing your proactive approach and independence.
✨Prepare for Technical Questions
Expect in-depth technical questions related to drug development processes and methodologies. Brush up on recent advancements in oncology therapeutics and be ready to discuss how you would apply your knowledge to the company's goals.
