Machine Learning Engineer | Omics | RNA | DNA | PyTorch | Hybrid, London
Machine Learning Engineer | Omics | RNA | DNA | PyTorch | Hybrid, London

Machine Learning Engineer | Omics | RNA | DNA | PyTorch | Hybrid, London

Full-Time 48000 - 84000 £ / year (est.) Home office (partial)
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At a Glance

  • Tasks: Join our ML team to build genomic models and train cutting-edge algorithms.
  • Company: We're a pioneering biotech firm revolutionising gene-editing through advanced machine learning.
  • Benefits: Enjoy a hybrid work model, collaborative culture, and opportunities for professional growth.
  • Why this job: Be part of a dynamic team tackling real-world challenges in plant sciences with innovative tech.
  • Qualifications: Postgraduate experience in ML, ideally with biological applications and familiarity with PyTorch.
  • Other info: Contribute to impactful projects while working alongside experts in the field.

The predicted salary is between 48000 - 84000 £ per year.

While gene-editing is becoming increasingly efficient, identifying which genes to edit and how remains a significant challenge. To overcome this bottleneck, we use cutting-edge deep learning to accurately and efficiently identify high-value genetic targets for gene-editing. Our approach draws inspiration from recent advancements in the drug discovery space, incorporating large language models (LLMs), transformers, and graph-based technologies to build a best-in-class discovery platform for plant sciences.

Our team is currently composed of 12 members, including ML engineers, data engineers, and bioinformaticians. We also have a remote, part-time intern conducting ML research. The team primarily works together in person at our office in London 4 days per week.

As part of the core ML team, you will help us build genomic foundation models. Your responsibilities could range from model training to data curation to evaluations. We welcome applicants with specific expertise who feel they could uniquely contribute to the training lifecycle of large, complex models. The ideal applicant will have experience using genomic data in a machine learning context. We are particularly interested in individuals with experience working with foundational generative models of DNA or transcriptomic data. However, our modelling efforts have a strong focus on multi-modality, so experience with or interest in other data modalities (e.g., text) is a plus.

Core Responsibilities
  • Contribution to the development of proprietary -omics models, including model training and evaluation development.
  • Recreation of state-of-the-art models from the scientific literature and benchmarking against internal models and evaluations.
Additional / Development Areas
  • Model deployment to ensure flexible and scalable inference access to the wider Data Science team.
  • Collaboration with the bioinformatics team to ingest, standardize, and QC data from multiple sources (internal and external) for use in training pipelines.
  • Support for the wider ML team on model development and commercial projects.
Core
  • Postgraduate experience (MSc or PhD) in ML with a demonstrated application to a biological domain.
  • Experience building modern ML architectures (e.g., transformers, diffusers) from scratch and applying them to real biological datasets.
  • Experience working with large-scale transcriptomic datasets, ideally from non-human organisms (though not required).
  • Experience with PyTorch, huggingface transformers, and diffusers.
  • Experience working with ML accelerators.
Nice-to-have
  • Relevant publications in reputable journals or contributions to open-source projects.
  • Exposure to and interest in probabilistic ML, causal ML, or active learning.
  • Experience with distributed model training (data and model parallelism).
  • Experience working on biological data curation, including data cleansing and preprocessing of -omics datasets.
  • Exposure to cloud-based ML orchestration frameworks such as Sagemaker and Vertex AI.
  • Experience with model deployment in an enterprise setting.

For immediate consideration please send your most up to date CV to.

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Contact Detail:

Enigma Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Machine Learning Engineer | Omics | RNA | DNA | PyTorch | Hybrid, London

✨Tip Number 1

Familiarise yourself with the latest advancements in deep learning, particularly in the context of genomics. Understanding how large language models and transformers are applied in gene-editing will give you a significant edge during discussions with our team.

✨Tip Number 2

Engage with the bioinformatics community by attending relevant conferences or webinars. Networking with professionals in this field can provide insights into current challenges and innovations, which could be beneficial when discussing your potential contributions to our projects.

✨Tip Number 3

Showcase any hands-on experience you have with PyTorch and other ML frameworks by working on personal projects or contributing to open-source initiatives. This practical knowledge will demonstrate your capability to build and deploy models effectively.

✨Tip Number 4

Prepare to discuss specific examples of how you've worked with multi-modal data in your previous roles. Highlighting your ability to integrate different data types will resonate well with our focus on developing comprehensive -omics models.

We think you need these skills to ace Machine Learning Engineer | Omics | RNA | DNA | PyTorch | Hybrid, London

Machine Learning Expertise
Deep Learning Frameworks (PyTorch)
Genomic Data Analysis
Model Training and Evaluation
Transformers and Diffusers Architecture
Data Curation and Quality Control
Large-Scale Transcriptomic Datasets Handling
Multi-Modality Data Integration
Collaboration with Bioinformatics Teams
Model Deployment Techniques
Cloud-Based ML Orchestration (e.g., Sagemaker, Vertex AI)
Experience with ML Accelerators
Probabilistic ML and Causal ML Knowledge
Active Learning Techniques
Publications in Reputable Journals or Open-Source Contributions

Some tips for your application 🫡

Tailor Your CV: Make sure your CV highlights relevant experience in machine learning, particularly with genomic data and the technologies mentioned in the job description, such as PyTorch and transformers. Use specific examples to demonstrate your expertise.

Craft a Compelling Cover Letter: Write a cover letter that explains why you are passionate about the role and how your background aligns with the company's mission. Mention any specific projects or experiences that relate to gene-editing and deep learning.

Showcase Relevant Projects: If you have worked on projects involving large-scale transcriptomic datasets or foundational generative models, be sure to include these in your application. Highlight your contributions and the impact of your work.

Highlight Collaboration Skills: Since the role involves working closely with bioinformaticians and other team members, emphasise your teamwork and collaboration skills. Provide examples of how you've successfully worked in multidisciplinary teams in the past.

How to prepare for a job interview at Enigma

✨Showcase Your Technical Skills

Be prepared to discuss your experience with machine learning frameworks, particularly PyTorch and transformers. Highlight any projects where you've built or trained models using genomic data, as this will demonstrate your relevant expertise.

✨Understand the Company’s Focus

Research the company’s approach to gene-editing and their use of deep learning in identifying genetic targets. Being able to articulate how your skills align with their mission will show that you are genuinely interested in the role.

✨Prepare for Problem-Solving Questions

Expect to face technical questions that assess your problem-solving abilities. Be ready to walk through your thought process on how you would tackle challenges related to model training and data curation in a biological context.

✨Demonstrate Collaboration Skills

Since the role involves working closely with bioinformaticians and other ML engineers, be sure to highlight your teamwork experiences. Discuss any collaborative projects you've worked on and how you contributed to achieving common goals.

Machine Learning Engineer | Omics | RNA | DNA | PyTorch | Hybrid, London
Enigma
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  • Machine Learning Engineer | Omics | RNA | DNA | PyTorch | Hybrid, London

    Full-Time
    48000 - 84000 £ / year (est.)

    Application deadline: 2027-05-24

  • E

    Enigma

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