Senior Scientist, Chemical Development

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.

At Immunocore, we recognize that our employees are our greatest asset. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.

Responsibilities include:

• Contributing to the development of characterisation methods for the company’s biopharmaceutical products, including peptide mapping (LC-MS/MS) and intact mass spectrometry analysis.
• Performing protein sequence and post translational modification identification, including glycosylation analysis.
• Designing and carrying out biochemical characterisation, chemical stability and comparability studies of biologics/drug products.
• Contributing to writing study protocols and reports.
• Independently testing and leading lines of investigation, proposing new experiments based on emerging data.
• Establishing priorities for own work and team-based projects; making decisions on prioritisation based on overall goals.
• Acting as a mentor to other colleagues, sharing scientific knowledge.
• Providing analysis of new techniques and theories from outside the company to advance operations.
• Ensuring that all laboratory records and information are up to date and recorded to the correct standard.
• Providing technical guidance on laboratory equipment usage.
• Communicating and presenting research findings at meetings with colleagues, senior management and partners.
• Adhering to safe working practices in laboratories according to Immunocore EHS policies.

Experience required:

• Experience of glycosylation analysis of recombinant proteins or antibodies.
• Experience in a bench-based biopharmaceutical laboratory environment.
• Experience with late stage/commercial biopharmaceutical assay development and characterisation.
• Experience in leading a small project team through a change in practice, including project management.
• Or MSc in biochemistry, biotechnology or related discipline.
• Desirable: PhD in related discipline.