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- Tasks: Lead research on gene-editing systems and analyze large metagenomic datasets.
- Company: Join a cutting-edge team focused on innovative bioinformatics solutions.
- Benefits: Work at the forefront of science with opportunities for growth and impact.
- Why this job: Be part of groundbreaking research in gene editing and therapeutic applications.
- Qualifications: Experience in bioinformatics and data analysis is essential.
- Other info: Exciting chance to contribute to transformative scientific advancements.
The predicted salary is between 48000 - 84000 £ per year.
Job Description
About the Role:
We are looking for an experienced and highly analytical Senior Bioinformatician/Data Scientist to join our research and development team. In this role, you will drive the discovery, development, and curation of gene-editing systems and mobile genetic elements (MGEs), with an emphasis on therapeutic applications. This position offers an exciting opportunity to work at the forefront of bioinformatics, particularly within large-scale metagenomic and microbiome data projects, as we explore new possibilities in gene-editing, viral integration, and secondary metabolite discovery.
Key Responsibilities:
- Lead research and curation efforts focused on gene-editing systems, moving beyond CRISPR screening to identify and annotate novel gene-editing mechanisms.
- Apply advanced bioinformatics methods to catalog and characterize diverse gene-editing systems, with a focus on their therapeutic potential.
- Identify, curate, and analyze MGEs and viral integration events within metagenomic datasets.
- Develop methods to track and characterize these elements, enhancing understanding of their roles in gene mobility, genomic instability, and therapeutic applications.
- Conduct comprehensive analyses on large metagenomic and microbiome datasets, utilizing robust computational tools to process and interpret complex data.
- Generate insights into the microbial ecology, gene function, and genomic context of potential therapeutic elements within microbial communities.
- Drive research with a therapeutic focus, identifying gene-editing systems or MGEs that can potentially be harnessed for human health applications.
- Collaborate with interdisciplinary teams to translate findings from metagenomic and gene-editing studies into viable therapeutic candidates.
- Nice to Have – Biosynthetic Gene Clusters (BGCs) and Secondary Metabolite Discovery:
- Conduct research in BGCs or secondary metabolite discovery, contributing to the exploration of bioactive compounds within microbial communities.
- Utilize bioinformatic tools to identify BGCs within metagenomic datasets, exploring secondary metabolites that may possess therapeutic properties.
Qualifications:
- PhD or Master’s in Bioinformatics, Computational Biology, Genomics, or a related field with strong expertise in gene-editing systems, MGEs, or viral integration research.
- Extensive experience in large-scale metagenomic or microbiome data analysis.
- Proven background in developing bioinformatic methods or pipelines for discovery and curation of gene-editing systems beyond traditional CRISPR applications.
- Knowledge of gene-editing therapeutic applications, MGE biology, and viral integration, with an interest in translational research.
- Proficiency in bioinformatics programming languages (Python, R, or similar) and experience with large data management and workflow development.
- Nice to have: Background in BGC or secondary metabolite discovery within metagenomic datasets.
This is a unique opportunity to play a critical role in pioneering therapeutic discoveries in gene editing and microbial genomics. If you’re passionate about advancing bioinformatics for impactful health applications, we would love to hear from you!
To apply, please submit your resume detailing relevant experience, and any supporting documents such as publications or project summaries. We look forward to seeing how you can help advance our research frontiers!
Senior Bioinformatician/Data Scientist - Gene Editing employer: Northreach
Contact Detail:
Northreach Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Bioinformatician/Data Scientist - Gene Editing
✨Tip Number 1
Make sure to showcase your experience with gene-editing systems and bioinformatics in your conversations. Highlight any specific projects you've worked on that relate to CRISPR or other novel mechanisms, as this will resonate well with our team.
✨Tip Number 2
Familiarize yourself with the latest trends in metagenomics and microbiome research. Being able to discuss recent advancements or breakthroughs in these areas during your interactions can demonstrate your passion and knowledge, making you a standout candidate.
✨Tip Number 3
Prepare to discuss your experience with large datasets and computational tools. We value candidates who can articulate their approach to analyzing complex data, so be ready to share specific examples of how you've tackled similar challenges in the past.
✨Tip Number 4
Network with professionals in the bioinformatics and gene-editing fields. Engaging with others in the industry can provide valuable insights and connections that may help you during the application process and beyond.
We think you need these skills to ace Senior Bioinformatician/Data Scientist - Gene Editing
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in bioinformatics and data science, particularly any work related to gene editing or metagenomic datasets. Use specific examples that demonstrate your analytical skills and familiarity with advanced computational tools.
Craft a Strong Cover Letter: In your cover letter, express your passion for bioinformatics and the therapeutic applications of gene editing. Mention specific projects or experiences that align with the responsibilities outlined in the job description, showcasing your ability to lead research efforts.
Highlight Technical Skills: Clearly list your technical skills related to bioinformatics, such as programming languages (e.g., Python, R), data analysis techniques, and any experience with large-scale datasets. This will help demonstrate your capability to handle the complex analyses required for the role.
Showcase Collaborative Experience: Since the role involves working within a research and development team, emphasize any previous collaborative projects. Discuss how you contributed to team goals and how your input led to successful outcomes in research initiatives.
How to prepare for a job interview at Northreach
✨Showcase Your Analytical Skills
Be prepared to discuss specific examples of how you've applied advanced bioinformatics methods in previous projects. Highlight your experience with large-scale metagenomic and microbiome datasets, as this will demonstrate your capability to handle the complexities of the role.
✨Understand Gene-Editing Mechanisms
Familiarize yourself with various gene-editing systems beyond CRISPR. Be ready to explain how you would approach identifying and annotating novel mechanisms, as this is a key responsibility of the position.
✨Discuss Your Research Experience
Prepare to talk about your past research and curation efforts, especially those related to mobile genetic elements (MGEs) and viral integration. This will show your potential employer that you have relevant experience and a strong understanding of the field.
✨Demonstrate Problem-Solving Abilities
Think of examples where you've developed innovative methods to track and characterize genetic elements. Discuss how you approached challenges in your previous work, as this will highlight your critical thinking and problem-solving skills.
