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- Tasks: Join a talented team to design and execute large-scale molecular genetic experiments.
- Company: Be part of a rapidly growing company making a positive impact on patients' lives.
- Benefits: Gain exposure to diverse skills and potential leadership opportunities in a dynamic environment.
- Why this job: Contribute to innovative research while shaping the company's culture and strategic direction.
- Qualifications: PhD with 3+ years in academia, biotech, or pharma; expertise in high-throughput assays required.
- Other info: Ideal for self-motivated individuals eager to learn and thrive in a fast-paced lab setting.
The predicted salary is between 43200 - 72000 £ per year.
We have an exciting opportunity for a talented Senior Scientist to contribute intellectually and experimentally to this endeavour. By joining, you will be part of an exceptionally talented team, gain exposure to a broad range of skills beyond your area of expertise, help shape our culture and strategic direction, and ultimately, make a positive impact on patients’ lives. As the company grows rapidly, there may be opportunities to supervise a small team.
Your Responsibilities
- Contribute intellectually and experimentally to the design and execution of large-scale molecular genetic experiments, including cell model characterisation, assay optimisation, and high-throughput screening.
- Develop, optimise, and implement functional assays to investigate gene function in disease-relevant contexts, with a focus on endothelial and fibroblast biology.
- Work closely with data scientists to develop robust data analysis pipelines.
- Contribute to the biological interpretation of screen hits and drive target validation efforts.
- Stay abreast of new gene-editing technologies and methodologies.
- Support laboratory operations in a start-up environment, contributing to shared responsibilities such as tissue culture maintenance and equipment upkeep.
Professionally, you have
- A PhD with at least 3 years of additional experience in academia, biotech, or pharma.
- Expertise in high-throughput cell assay development, including adherent and suspension cells.
- Strong experience in functional assays related to either endothelial OR fibroblast biology, specifically: Endothelial cell functional assays, including angiogenesis, EndoMT (Endothelial-to-Mesenchymal Transition), and tube formation assays; Fibroblast functional assays, including extracellular matrix (ECM) deposition and contraction assays.
- Experience leading the day-to-day operations of large-scale genetic or chemical screens in arrayed and/or pooled formats.
- At least two years of hands-on experience applying the latest CRISPR/Cas genome-editing approaches, including nucleofection and/or lentiviral transductions.
- Proven ability to deliver results within tight timelines.
Desirable:
- Experience with liquid handling, automation, FACS, and/or automated high-content microscopy.
- Experience working in interdisciplinary teams, particularly with computational scientists.
- Broad expertise in molecular biology, including molecular cloning.
Your Attributes
- Excellent attention to detail, analytical and critical thinking skills.
- Strong team-working abilities and effective communication with scientists across disciplines.
- Self-motivated with an inquisitive nature and eagerness to learn.
- Ability to work in a fast-paced, data-driven environment with shifting priorities.
- Willingness to contribute to operational aspects of a growing laboratory.
Senior Scientist- Genomics employer: ZipRecruiter
Contact Detail:
ZipRecruiter Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Senior Scientist- Genomics
✨Tip Number 1
Network with professionals in the genomics field, especially those who have experience in high-throughput cell assay development. Attend relevant conferences or webinars to meet potential colleagues and learn about the latest advancements in gene-editing technologies.
✨Tip Number 2
Familiarise yourself with the specific functional assays mentioned in the job description, such as endothelial cell functional assays and fibroblast functional assays. Consider conducting independent research or projects that demonstrate your expertise in these areas.
✨Tip Number 3
Showcase your ability to work in interdisciplinary teams by collaborating on projects that involve both experimental and computational aspects. Highlight any experiences where you successfully partnered with data scientists to develop data analysis pipelines.
✨Tip Number 4
Stay updated on the latest CRISPR/Cas genome-editing techniques and methodologies. Engage in online courses or workshops that focus on advanced gene-editing approaches to enhance your practical skills and knowledge.
We think you need these skills to ace Senior Scientist- Genomics
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights your relevant experience in genomics, particularly your expertise in high-throughput cell assay development and functional assays related to endothelial or fibroblast biology. Use specific examples to demonstrate your skills.
Craft a Compelling Cover Letter: In your cover letter, express your enthusiasm for the role and the company. Discuss how your background aligns with their needs, particularly your experience with CRISPR/Cas genome-editing approaches and your ability to work in interdisciplinary teams.
Highlight Relevant Projects: Include specific projects or research that showcase your contributions to molecular genetic experiments and data analysis pipelines. This will help illustrate your hands-on experience and problem-solving abilities.
Showcase Soft Skills: Don't forget to mention your soft skills such as attention to detail, analytical thinking, and teamwork. These attributes are crucial for a role that involves collaboration with scientists across various disciplines.
How to prepare for a job interview at ZipRecruiter
✨Showcase Your Expertise
Be prepared to discuss your specific experience in high-throughput cell assay development and functional assays related to endothelial or fibroblast biology. Highlight any relevant projects you've worked on, especially those that demonstrate your ability to deliver results under tight timelines.
✨Demonstrate Team Collaboration
Since the role involves working closely with data scientists and interdisciplinary teams, be ready to share examples of how you've successfully collaborated in the past. Emphasise your communication skills and how you can bridge the gap between different scientific disciplines.
✨Stay Updated on Technologies
Familiarise yourself with the latest gene-editing technologies and methodologies, particularly CRISPR/Cas approaches. During the interview, express your enthusiasm for staying current in the field and how you plan to integrate new techniques into your work.
✨Prepare for Problem-Solving Questions
Expect questions that assess your analytical and critical thinking skills. Prepare to discuss how you've approached complex problems in previous roles, particularly in designing and executing large-scale molecular genetic experiments.
