Find a job 
Featured Companies 
Featured Universities 
For Companies At a Glance
- Tasks: Lead innovative drug development projects and guide teams in ADME/PK strategies.
- Company: Join a cutting-edge biotech firm in Cambridge with a focus on global health impact.
- Benefits: Enjoy competitive salary, bonuses, private medical, and 26 days leave plus wellness initiatives.
- Why this job: Be part of a dynamic team shaping the future of medicine in high-growth therapeutic areas.
- Qualifications: 3+ years in lead optimisation, strong ADME/PK knowledge, and excellent communication skills required.
- Other info: Work in a state-of-the-art R&D centre within the vibrant Cambridge science cluster.
The predicted salary is between 43200 - 72000 £ per year.
An exciting opportunity has opened up for a DMPK Senior or Lead Scientist to join a well-funded, innovation-driven biotech company based in Cambridge, UK. You’ll play a key role in shaping ADME/PK strategy across early-stage discovery projects, using cutting-edge structure-based design approaches to help progress novel candidates into the clinic. The role spans multiple high-growth therapeutic areas including CNS, immunology, GI, and rare diseases.
What you’ll do:
- Design and interpret in vitro ADME and in vivo PK studies
- Guide medicinal chemistry teams with human PK predictions and data insights
- Identify DMPK-related risks and shape mitigation strategies
- Support PK/PD modelling, dose projections, and development transition
We’re looking for:
- 3+ years in lead optimisation or preclinical development
- Strong technical grounding in ADME/PK principles
- Solid understanding of PhysChem properties and their impact on drug design
- Confident communicator in cross-functional, fast-paced project teams
- Experience with PBPK or PK analysis tools (e.g. GastroPlus, WinNonlin) is a plus
What’s on offer:
- Join a biotech with 30+ active drug programs and world-class scientific teams
- Competitive salary + bonus, private medical, eligibility for restricted stock units, and enhanced benefits
- 26 days leave (+ option to buy), strong focus on wellbeing
- Work at a state-of-the-art R&D centre in the Cambridge science cluster
Interested? Apply now or reach out for a confidential chat.
DMPK Senior / Lead Scientist employer: Talent Therapeutics
Contact Detail:
Talent Therapeutics Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land DMPK Senior / Lead Scientist
✨Tip Number 1
Network with professionals in the biotech industry, especially those working in DMPK or related fields. Attend relevant conferences or seminars in Cambridge to meet potential colleagues and learn about the latest trends and technologies.
✨Tip Number 2
Familiarise yourself with the specific ADME/PK strategies used by the company. Research their current projects and therapeutic areas to demonstrate your knowledge and enthusiasm during any discussions or interviews.
✨Tip Number 3
Prepare to discuss your experience with lead optimisation and preclinical development in detail. Be ready to share specific examples of how you've contributed to similar projects and the impact of your work on drug design.
✨Tip Number 4
Showcase your communication skills by engaging with cross-functional teams in your current or previous roles. Highlight instances where you successfully collaborated with medicinal chemistry teams or other departments to achieve project goals.
We think you need these skills to ace DMPK Senior / Lead Scientist
Some tips for your application 🫡
Tailor Your CV: Make sure your CV highlights relevant experience in DMPK, ADME/PK principles, and any specific tools you've used like GastroPlus or WinNonlin. Emphasise your role in lead optimisation or preclinical development.
Craft a Compelling Cover Letter: In your cover letter, express your enthusiasm for the biotech industry and the specific role. Mention how your skills align with the company's needs, particularly in shaping ADME/PK strategies and working in cross-functional teams.
Showcase Your Communication Skills: Since the role requires confident communication in fast-paced project teams, provide examples in your application of how you've successfully collaborated with others and communicated complex data insights.
Highlight Relevant Projects: If you have experience with specific therapeutic areas mentioned in the job description, such as CNS or immunology, be sure to include these in your application. Discuss any projects where you identified DMPK-related risks and developed mitigation strategies.
How to prepare for a job interview at Talent Therapeutics
✨Showcase Your Technical Expertise
Make sure to highlight your strong grounding in ADME/PK principles during the interview. Be prepared to discuss specific projects where you've applied these principles, as well as any experience with PBPK or PK analysis tools like GastroPlus or WinNonlin.
✨Demonstrate Cross-Functional Communication Skills
Since the role involves working in cross-functional teams, it's crucial to showcase your communication skills. Prepare examples of how you've effectively collaborated with medicinal chemistry teams or other departments to achieve project goals.
✨Prepare for Scenario-Based Questions
Expect scenario-based questions that assess your ability to identify DMPK-related risks and develop mitigation strategies. Think of past experiences where you successfully navigated similar challenges and be ready to share those insights.
✨Express Your Passion for Innovation
This biotech company values innovation, so convey your enthusiasm for cutting-edge research and development. Discuss any relevant experiences where you've contributed to innovative drug design or early-stage discovery projects.
