Principal Scientist

Principal Scientist

Oxford Full-Time 43200 - 72000 £ / year (est.) No home office possible
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At a Glance

  • Tasks: Lead innovative cancer research and design impactful studies in a dynamic team.
  • Company: Join a cutting-edge biotechnology company dedicated to developing anti-cancer therapies.
  • Benefits: Enjoy bonuses, flexible hours, private medical insurance, and a pension plan.
  • Why this job: Make a real difference in cancer treatment while collaborating with top scientists in the field.
  • Qualifications: PhD in a relevant field with hands-on experience in oncology and tumor microenvironment.
  • Other info: Must have the right to work in the UK; active animal license is a plus.

The predicted salary is between 43200 - 72000 £ per year.

CK Group are recruiting for a proactive Principal Scientist, with a strong background in cancer biology and tumour microenvironment, to join a growing biotechnology company, on a permanent basis, to be based in Oxford.

This is a great opportunity for a highly motivated scientist, with a commitment to research on anti-cancer therapies to take responsibility in a fast-paced environment, working within an interdisciplinary team to develop new cancer treatments.

The Role:

Contributing to strategic R&D goals you will be designing, managing, and performing oncolytic immunotherapy studies to support candidate development and inform clinical strategy. The successful candidate will focus on the actions and influence on the tumour microenvironment, and application in new tumour indications.

Your Responsibilities:

  • Responsible for study plan design and approval, as well as overseeing data collection, analysis, reporting and for the final conclusions from the study report including sign off.
  • Design and execution of R&D projects.
  • Act as independent scientist reviewer and sign off lab books, verifying the calculations, and approving SOPs.
  • Act as mentor and supervisor.
  • Contributing to presentations, reports and regulatory filings.

Your Background:

  • PhD degree or equivalent in a relevant scientific discipline with strong industry expertise in cancer biology and scientific acumen in tumour microenvironment.
  • Significant level of hands on experience in performing in-vivo experiments in oncology models for drug discovery (preferably in humanised immune mouse models).
  • Experience performing i.t. / i.v / i.p injections.
  • Good knowledge of Mode of action, Tumour Micro-environment and spatial transcriptomics/RNA scope.
  • Technical experience on qPCR, RNA/DNA extractions, ELISA and cell-based assays.
  • Active animal licence from the Home Office (DESIRABLE).
  • Experience of in vivo imaging (e.g. bioluminescence), IHC / flow cytometry/ multiplex immunofluorescence.
  • Skilled in bioinformatic analysis.

Benefits:

  • Bonus.
  • Pension.
  • Private Medical Insurance.
  • Flexible working hours.

Apply:

It is essential that applicants hold entitlement to work in the UK. Please quote job reference 121 585 in all correspondence. #J-18808-Ljbffr

Principal Scientist employer: Royal Society of Chemistry

CK Group is an exceptional employer, offering a dynamic and collaborative work environment in the heart of Oxford, where innovation thrives. As a Principal Scientist, you will not only contribute to groundbreaking cancer research but also benefit from a comprehensive package that includes bonuses, private medical insurance, and flexible working hours, all designed to support your professional growth and work-life balance. Join us to be part of a passionate team dedicated to developing transformative anti-cancer therapies while enjoying the unique advantages of working in a vibrant biotechnology hub.
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Contact Detail:

Royal Society of Chemistry Recruiting Team

StudySmarter Expert Advice 🤫

We think this is how you could land Principal Scientist

✨Tip Number 1

Make sure to highlight your hands-on experience with in-vivo experiments, especially in oncology models. This is crucial for the Principal Scientist role, so be ready to discuss specific projects where you've applied these skills.

✨Tip Number 2

Familiarize yourself with the latest research and developments in the tumour microenvironment and oncolytic immunotherapy. Being able to discuss current trends and how they relate to the company's goals will show your commitment and expertise.

✨Tip Number 3

Prepare to demonstrate your ability to work within an interdisciplinary team. Think of examples from your past experiences where collaboration led to successful outcomes in research projects.

✨Tip Number 4

If you have experience with bioinformatic analysis, be ready to discuss specific tools and methodologies you've used. This skill is increasingly important in cancer research, and showcasing it can set you apart from other candidates.

We think you need these skills to ace Principal Scientist

Cancer Biology Expertise
Tumour Microenvironment Knowledge
Oncolytic Immunotherapy Design
In Vivo Experimentation
Drug Discovery Techniques
Injection Techniques (i.t., i.v., i.p.)
Spatial Transcriptomics
qPCR Proficiency
RNA/DNA Extraction Skills
ELISA and Cell-Based Assays
In Vivo Imaging Techniques
IHC and Flow Cytometry
Multiplex Immunofluorescence
Bioinformatics Analysis
Data Collection and Analysis
Regulatory Filing Experience
Mentoring and Supervisory Skills

Some tips for your application 🫡

Tailor Your CV: Make sure your CV highlights your PhD and relevant experience in cancer biology and the tumour microenvironment. Emphasize any hands-on experience with in-vivo experiments and specific techniques mentioned in the job description.

Craft a Strong Cover Letter: In your cover letter, express your passion for anti-cancer therapies and your commitment to research. Discuss how your background aligns with the responsibilities of the role, particularly in designing and managing oncolytic immunotherapy studies.

Highlight Relevant Skills: Clearly outline your technical skills related to qPCR, RNA/DNA extractions, ELISA, and cell-based assays. Mention any experience with bioinformatic analysis and in vivo imaging techniques, as these are crucial for the position.

Showcase Leadership Experience: If you have experience mentoring or supervising others, be sure to include this in your application. Highlight any instances where you acted as an independent reviewer or contributed to presentations and reports.

How to prepare for a job interview at Royal Society of Chemistry

✨Showcase Your Expertise in Cancer Biology

Make sure to highlight your strong background in cancer biology and the tumour microenvironment during the interview. Be prepared to discuss specific projects or research that demonstrate your expertise and how it aligns with the company's goals.

✨Discuss Your Experience with In-Vivo Experiments

Since hands-on experience in performing in-vivo experiments is crucial for this role, be ready to share detailed examples of your work in oncology models. Discuss the techniques you've used, such as i.t., i.v., or i.p. injections, and any relevant outcomes.

✨Prepare for Technical Questions

Expect technical questions related to your knowledge of the tumour microenvironment, spatial transcriptomics, and RNA scope. Brush up on these topics and be ready to explain complex concepts clearly and confidently.

✨Demonstrate Leadership and Mentorship Skills

As a Principal Scientist, you'll be expected to mentor and supervise others. Prepare to discuss your leadership style and provide examples of how you've successfully guided teams or individuals in past roles.

Principal Scientist
Royal Society of Chemistry
R
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