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- Tasks: Lead the purification and structural characterization of small molecules from plant extracts.
- Company: Join HotHouse Therapeutics, a pioneer in natural product drug discovery.
- Benefits: Collaborate with a dynamic team and contribute to innovative projects.
- Why this job: Be part of a revolutionary approach to drug discovery with real-world impact.
- Qualifications: PhD in Chemistry or related field; experience with analytical techniques required.
- Other info: Work in a multidisciplinary team and develop your ideas independently.
The predicted salary is between 36000 - 60000 £ per year.
Scientist: Natural Product Chemistry
About the Company
HotHouse Therapeutics is a first mover company revolutionising natural product drug discovery. We discover the tools which plants have evolved to synthesise bioactive small molecules and then redeploy them to synthesise new-to-nature small molecule drugs. This is an exciting opportunity to join our growing and ambitious team as a natural product chemist.
The candidate will lead the purification and structural characterisation of promising small molecules from plant extracts. They will collaborate with others as part of biosynthetic-production pipeline. This will involve the use of techniques on a range of scales, from preparative to analytical. The candidate will be required to develop and optimize the purification process to purify mg-scale quantities of compounds for further testing, working with other laboratory-based scientists along with informaticians.
Responsibilities
· Extracting and purifying small molecules from complex plant material
· Characterising molecular structures
· Optimising purification pipelines and methods
· Collaborate with the wider scientific team to deliver projects
Essential
· PhD in Chemistry or a related field
· Experience using analytical techniques, such LC-MS, HPLC and NMR
· Ability to utilise preparative and semi-preparative HPLC to purify targets
· Strong problem-solving skills
· Ability to work independently and develop ideas
· Ability to work in a multidisciplinary team
· Excellent presentation and communication skills
Desirable
· Experience using metabolomics to analyse identify target compounds
· Experience purifying compounds from plant extracts
· Experience purifying targets with low starting concentrations
Enquiries and Applications to careers@hothousetx.com
Chemist: Natural Products employer: HotHouse Therapeutics
Contact Detail:
HotHouse Therapeutics Recruiting Team
StudySmarter Expert Advice 🤫
We think this is how you could land Chemist: Natural Products
✨Tip Number 1
Familiarize yourself with the latest advancements in natural product chemistry. This will not only help you understand the field better but also allow you to engage in meaningful conversations during interviews.
✨Tip Number 2
Network with professionals in the field of natural product chemistry. Attend relevant conferences or webinars where you can meet potential colleagues and learn about the latest research, which could give you an edge.
✨Tip Number 3
Prepare to discuss your experience with analytical techniques like LC-MS, HPLC, and NMR in detail. Be ready to provide examples of how you've used these methods in past projects.
✨Tip Number 4
Showcase your problem-solving skills by preparing case studies or examples from your previous work where you successfully optimized purification processes or collaborated effectively with a team.
We think you need these skills to ace Chemist: Natural Products
Some tips for your application 🫡
Understand the Company: Familiarize yourself with HotHouse Therapeutics and their mission in natural product drug discovery. This will help you tailor your application to align with their goals.
Highlight Relevant Experience: Emphasize your PhD in Chemistry and any relevant experience with analytical techniques like LC-MS, HPLC, and NMR. Be specific about your hands-on experience with purification processes.
Showcase Problem-Solving Skills: Provide examples of how you've tackled challenges in previous projects. Highlight your ability to work independently and develop innovative ideas in a laboratory setting.
Craft a Strong Cover Letter: Write a compelling cover letter that outlines your passion for natural product chemistry and your desire to contribute to the team at HotHouse Therapeutics. Make sure to mention your collaborative spirit and communication skills.
How to prepare for a job interview at HotHouse Therapeutics
✨Showcase Your Technical Skills
Be prepared to discuss your experience with analytical techniques like LC-MS, HPLC, and NMR. Highlight specific projects where you successfully utilized these methods to purify and characterize small molecules.
✨Demonstrate Problem-Solving Abilities
Prepare examples of challenges you've faced in previous roles and how you overcame them. This will showcase your strong problem-solving skills, which are essential for optimizing purification processes.
✨Emphasize Collaboration Experience
Since the role involves working within a multidisciplinary team, be ready to share experiences where you collaborated effectively with others. Discuss how you contributed to team projects and the outcomes achieved.
✨Communicate Clearly and Confidently
Excellent presentation and communication skills are crucial. Practice explaining complex scientific concepts in a clear and concise manner, as you may need to present your findings or ideas during the interview.
